DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ekavianty Prajatelistia | - |
dc.contributor.author | Naresh D. Sanandiya | - |
dc.contributor.author | Andrieanto Nurrochman | - |
dc.contributor.author | Fresty Marseli | - |
dc.contributor.author | CHOY, SEUNGHWAN | - |
dc.contributor.author | HWANG, DONG SOO | - |
dc.date.accessioned | 2020-12-08T08:50:16Z | - |
dc.date.available | 2020-12-08T08:50:16Z | - |
dc.date.created | 2020-09-29 | - |
dc.date.issued | 2021-01-01 | - |
dc.identifier.issn | 0144-8617 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/104538 | - |
dc.description.abstract | Biopolymer-based membranes are at the forefront of the guided bone regeneration (GBR) in orthopaedics and dentistry, which prevent fast-growing soft tissue migration to the defected alveolar ridge or implants and allow the bone regeneration. In this study, we fabricated a novel Janus -two-faced, GBR membrane composed of a chitin nanofiber face for bone regeneration and a cell membrane mimetic antifouling 2-Methacryloyloxyethyl phosphorylcholine (MPC) polymeric face for suppressing the migration of the soft tissue. In vitro cell study showed a higher cell proliferation rate of osteoblast cells on the chitin nanofiber surface and a lower proliferation rate of fibroblasts cells on the antifouling MPC side. An increased of Alkaline Phosphatase (ALP) rate was observed in the chitin nanofiber face, indicating the ability to maintain proliferation and differentiation of osteogenic cells. These results suggest the biomimetic Janus chitin membrane may have the potential to develop as an advance GBR membrane. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.relation.isPartOf | CARBOHYDRATE POLYMERS | - |
dc.subject | 2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE | - |
dc.subject | ADHESION | - |
dc.subject | CHITOSAN | - |
dc.subject | HYDROGEL | - |
dc.subject | COHESION | - |
dc.subject | BARRIER | - |
dc.title | Biomimetic Janus chitin nanofiber membrane for potential guided bone regeneration application | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.carbpol.2020.117032 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | CARBOHYDRATE POLYMERS, v.251 | - |
dc.identifier.wosid | 000582801500046 | - |
dc.citation.title | CARBOHYDRATE POLYMERS | - |
dc.citation.volume | 251 | - |
dc.contributor.affiliatedAuthor | CHOY, SEUNGHWAN | - |
dc.contributor.affiliatedAuthor | HWANG, DONG SOO | - |
dc.identifier.scopusid | 2-s2.0-85090963856 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | 2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE | - |
dc.subject.keywordPlus | ADHESION | - |
dc.subject.keywordPlus | CHITOSAN | - |
dc.subject.keywordPlus | HYDROGEL | - |
dc.subject.keywordPlus | COHESION | - |
dc.subject.keywordPlus | BARRIER | - |
dc.subject.keywordAuthor | Chitin nanofiber | - |
dc.subject.keywordAuthor | Guided bone regeneration | - |
dc.subject.keywordAuthor | Anti-fouling | - |
dc.subject.keywordAuthor | MPC | - |
dc.subject.keywordAuthor | Biomimetic membrane | - |
dc.subject.keywordAuthor | Phosphorylcholine | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.