DC Field | Value | Language |
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dc.contributor.author | Su, Bodan | - |
dc.contributor.author | Zhang, Xi | - |
dc.contributor.author | Li, Li | - |
dc.contributor.author | Abbas, Sammar | - |
dc.contributor.author | Yu, Meng | - |
dc.contributor.author | Cui, Yaning | - |
dc.contributor.author | Baluska, Frantisek | - |
dc.contributor.author | Hwang, Inhwan | - |
dc.contributor.author | Shan, Xiaoyi | - |
dc.contributor.author | Lin, Jinxing | - |
dc.date.accessioned | 2021-06-14T01:50:26Z | - |
dc.date.available | 2021-06-14T01:50:26Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 1674-2052 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/106702 | - |
dc.description.abstract | Growth and immunity are opposing processes that compete for cellular resources, and proper resource allocation is crucial for plant survival. BSK1 plays a key role in the regulation of both growth and immunity by associating with BRI1 and FLS2, respectively. However, it remains unclear how two antagonistic signals co-opt BSK1 to induce signal-specific activation. Here we show that the dynamic spatial reorganization of BSK1 within the plasma membrane underlies the mechanism of signal-specific activation for growth or immunity. Resting BSK1 localizes to membrane rafts as complexes. Unlike BSK1-associated FLS2 and BRI1, flg22 or exogenous brassinosteroid (BR) treatment did not decrease BSK1 levels at the plasma membrane (PM) but rather induced BSK1 multimerization and dissociation from FLS2/BSK1 or BRI1/BSK1, respectively. Moreover, flg22-activated BSK1 translocated from membrane rafts to non-membrane-raft regions, whereas BR-activated BSK1 remained in membrane rafts. When applied together with flg22, BR suppressed various flg22-induced BSK1 activities such as BSK1 dissociation from FLS2/BSK1, BSK1 interaction with MAPKKK5, and BSK translocation together with MAPKKK5. Taken together, this study provides a unique insight into how the precise control of BSK1 spatiotemporal organization regulates the signaling specificity to balance plant growth and immunity. | - |
dc.language | English | - |
dc.publisher | CELL PRESS | - |
dc.relation.isPartOf | MOLECULAR PLANT | - |
dc.title | Dynamic spatial reorganization of BSK1 complexes in the plasma membrane underpins signal-specific activation for growth and immunity | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.molp.2021.01.019 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | MOLECULAR PLANT, v.14, no.4, pp.588 - 603 | - |
dc.identifier.wosid | 000637322000012 | - |
dc.citation.endPage | 603 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 588 | - |
dc.citation.title | MOLECULAR PLANT | - |
dc.citation.volume | 14 | - |
dc.contributor.affiliatedAuthor | Hwang, Inhwan | - |
dc.identifier.scopusid | 2-s2.0-85101988463 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | BSK1 | - |
dc.subject.keywordAuthor | dynamic | - |
dc.subject.keywordAuthor | spatiotemporal organization | - |
dc.subject.keywordAuthor | membrane rafts | - |
dc.subject.keywordAuthor | growth and immunity | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Plant Sciences | - |
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