Enhancing biomass and ethanol production by increasing NADPH production in Synechocystis sp. PCC 3803
SCIE
SCOPUS
- Title
- Enhancing biomass and ethanol production by increasing NADPH production in Synechocystis sp. PCC 3803
- Authors
- Yun-Nam Choi; Park, JM
- Date Issued
- 2016-08
- Publisher
- ELSEVIER
- Abstract
- This study demonstrates that increased NADPH production can improve biomass and ethanol production in cyanobacteria. We over-expressed the endogenous zwf gene, which encodes glucose-6-phosphate dehydrogenase of pentose phosphate pathway, in the model cyanobacterium Synechocystis sp. PCC 6803. zwf over-expression resulted in increased NADPH production, and promoted biomass production compared to the wild type in both autotrophic and mixotrophic conditions. Ethanol production pathway including NADPH-dependent alcohol dehydrogenase was also integrated with and without zwf overexpression. Excessive NADPH production by zwf over-expression could improve both biomass and ethanol production in the autotrophic conditions. (C) 2016 Elsevier Ltd. All rights reserved.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/107782
- DOI
- 10.1016/J.BIORTECH.2016.02.056
- ISSN
- 0960-8524
- Article Type
- Article
- Citation
- Bioresource Technology, vol. 213, no. 213, page. 54 - 57, 2016-08
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.