Aging of hair follicle stem cells and their niches
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SCOPUS
KCI
- Title
- Aging of hair follicle stem cells and their niches
- Authors
- HANSAEM JANG; YEMIN JO; JUNG HYUN LEE; CHOI, SEKYU
- Date Issued
- 2023-01
- Publisher
- 생화학분자생물학회
- Abstract
- Hair follicles in the skin undergo cyclic rounds of regeneration, degeneration, and rest throughout life. Stem cells residing in hair follicles play a pivotal role in maintaining tissue homeostasis and hair growth cycles. Research on hair follicle aging and age-related hair loss has demonstrated that a decline in hair follicle stem cell (HFSC) activity with aging can decrease the regeneration capacity of hair follicles. This review summarizes our understanding of how age-associated HFSC intrinsic and extrinsic mechanisms can induce HFSC aging and hair loss. In addition, we discuss approaches developed to attenuate ageassociated changes in HFSCs and their niches, thereby promoting hair regrowth.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/115522
- DOI
- 10.5483/BMBRep.2022-0183
- ISSN
- 1976-6696
- Article Type
- Article
- Citation
- BMB Reports, vol. 56, no. 1, page. 2 - 9, 2023-01
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- There are no files associated with this item.
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