REGIOSELECTIVE OXIRANE RING-OPENING OF TRANS-2,3-EPOXY ALCOHOLS WITH ARYLALUMINUM COMPLEXES
SCIE
- Title
- REGIOSELECTIVE OXIRANE RING-OPENING OF TRANS-2,3-EPOXY ALCOHOLS WITH ARYLALUMINUM COMPLEXES
- Authors
- AHN, KH; HAN, DS; JIN, CS; KANG, DH; KIM, DH; KIM, JS; SHIN, YS
- Date Issued
- 1992-04
- Publisher
- GEORG THIEME VERLAG KG
- Abstract
- Treatment of trans-2,3-epoxy alcohols 1, activated by triethylaluminum, with arylaluminum complexes 3 caused a regioselective ring-opening reaction at the 3-position to yield 3-aryl-1,2-alkanediols 4 in moderate yields. The activation of the epoxY ring by coordination with a Lewis acid appears to be essential for obtaining the desired product in a reasonable yield. While bulky substituents at the 3-position lowered the regioselectivity, a methoxy or methylenedioxy moiety on the arylaluminum complex 3 improved the regioselectivity drastically.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/12955
- ISSN
- 0936-5214
- Article Type
- Article
- Citation
- SYNLETT, no. 4, page. 306 - 308, 1992-04
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- There are no files associated with this item.
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