A Perspective on the Stereodefined N,O-Acetals: Synthesis and Potential Applications
SCIE
SCOPUS
- Title
- A Perspective on the Stereodefined N,O-Acetals: Synthesis and Potential Applications
- Authors
- Kim, H; Rhee, YH
- Date Issued
- 2012-12
- Publisher
- GEORG THIEME VERLAG KG
- Abstract
- Developing chemical reactions that rapidly introduce molecular diversity in a controlled manner represents a prime goal in synthetic organic chemistry. In this regard, our recent studies on the asymmetric synthesis and utilization of stereodefined N,O-acetal opens up a conceptually new methodology. The synthesis of labile N,O-acetals was accomplished by highly efficient and chemoselective Pd-catalyzed asymmetric hydroamination of alkoxyallenes. Furthermore, the utility of the stereodefined N,O-acetals as a stereodiversity-generating element was established by the gold-catalyzed cycloisomerization. In addition to these results, new aspects of the N,O-acetals as diversity-generating elements are also discussed.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/12961
- DOI
- 10.1055/S-0032-1317478
- ISSN
- 0936-5214
- Article Type
- Article
- Citation
- SYNLETT, no. 20, page. 2875 - 2879, 2012-12
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.