DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lei Li | - |
dc.contributor.author | Jin-Feng Zhao | - |
dc.contributor.author | Nayoun Won | - |
dc.contributor.author | Ho Jin | - |
dc.contributor.author | Kim, S | - |
dc.contributor.author | Ji-Yao Chen | - |
dc.date.accessioned | 2015-07-07T19:08:35Z | - |
dc.date.available | 2015-07-07T19:08:35Z | - |
dc.date.created | 2013-03-08 | - |
dc.date.issued | 2012-07-12 | - |
dc.identifier.issn | 1931-7573 | - |
dc.identifier.other | 2015-OAK-0000026980 | en_US |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/13124 | - |
dc.description.abstract | Sulfonated aluminum phthalocyanines (AlPcSs), commonly used photosensitizers for photodynamic therapy of cancers (PDT), were conjugated with amine-dihydrolipoic acid-coated quantum dots (QDs) by electrostatic binding, achieving 70 AlPcSs per QD. The AlPcS-QD conjugates can utilize the intense light absorptions of conjugated QDs to indirectly excite AlPcSs producing singlet oxygen via fluorescence resonance energy transfer (FRET), demonstrating a new excitation model for PDT. The AlPcS-QD conjugates easily penetrated into human nasopharyngeal carcinoma cells and carried out the FRET in cells, with efficiency around 80%. Under the irradiation of a 532-nm laser, which is at the absorption region of QDs but not fit for the absorption of AlPcSs, the cellular AlPcS-QD conjugates can destroy most cancer cells via FRET-mediated PDT, showing the potential of this new strategy for PDT. | - |
dc.description.statementofresponsibility | open | en_US |
dc.language | English | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | NANOSCALE RESEARCH LETTERS | - |
dc.rights | BY_NC_ND | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.0/kr | en_US |
dc.subject | uantum dot | - |
dc.subject | Aluminum phthalocyanine | - |
dc.subject | Fluorescence resonance energy transfer | - |
dc.subject | Photodynamic therapy of cancers | - |
dc.subject | SINGLET OXYGEN | - |
dc.subject | GOLD NANOPARTICLES | - |
dc.subject | FRET MICROSCOPY | - |
dc.subject | LIVING CELLS | - |
dc.subject | THERAPY | - |
dc.subject | WATER | - |
dc.subject | GENERATION | - |
dc.subject | ANION | - |
dc.subject | MICE | - |
dc.title | Quantum dot-aluminum phthalocyanine conjugates perform photodynamic reactions to kill cancer cells via fluorescence resonance energy transfer | - |
dc.type | Article | - |
dc.contributor.college | 화학과 | en_US |
dc.identifier.doi | 10.1186/1556-276X-7-386 | - |
dc.author.google | Li, L | en_US |
dc.author.google | Zhao, JF | en_US |
dc.author.google | Won, N | en_US |
dc.author.google | Jin, H | en_US |
dc.author.google | Kim, S | en_US |
dc.author.google | Chen, JY | en_US |
dc.relation.volume | 7 | en_US |
dc.relation.startpage | 386 | en_US |
dc.contributor.id | 10149571 | en_US |
dc.relation.journal | NANOSCALE RESEARCH LETTERS | en_US |
dc.relation.index | SCI급, SCOPUS 등재논문 | en_US |
dc.relation.sci | SCI | en_US |
dc.collections.name | Journal Papers | en_US |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | NANOSCALE RESEARCH LETTERS, v.7, pp.386 | - |
dc.identifier.wosid | 000319010500001 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.startPage | 386 | - |
dc.citation.title | NANOSCALE RESEARCH LETTERS | - |
dc.citation.volume | 7 | - |
dc.contributor.affiliatedAuthor | Kim, S | - |
dc.identifier.scopusid | 2-s2.0-84866106511 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 60 | - |
dc.description.scptc | 45 | * |
dc.date.scptcdate | 2018-10-274 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | SINGLET OXYGEN | - |
dc.subject.keywordPlus | FRET MICROSCOPY | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | GENERATION | - |
dc.subject.keywordPlus | ANION | - |
dc.subject.keywordAuthor | Quantum dot | - |
dc.subject.keywordAuthor | Aluminum phthalocyanine | - |
dc.subject.keywordAuthor | Fluorescence resonance energy transfer | - |
dc.subject.keywordAuthor | Photodynamic therapy of cancers | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
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