DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, SH | - |
dc.contributor.author | An, HS | - |
dc.contributor.author | Jung, YW | - |
dc.contributor.author | Lee, EJ | - |
dc.contributor.author | Lee, HY | - |
dc.contributor.author | Choi, ES | - |
dc.contributor.author | An, SW | - |
dc.contributor.author | Son, H | - |
dc.contributor.author | Lee, SJ | - |
dc.contributor.author | Kim, JB | - |
dc.contributor.author | Min, KJ | - |
dc.date.accessioned | 2016-03-31T07:37:28Z | - |
dc.date.available | 2016-03-31T07:37:28Z | - |
dc.date.created | 2015-02-04 | - |
dc.date.issued | 2014-04 | - |
dc.identifier.issn | 1389-5729 | - |
dc.identifier.other | 2014-OAK-0000031678 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/13834 | - |
dc.description.abstract | Viscum album coloratum (Korean mistletoe) is a semi-parasitic plant that grows on various trees and has a variety of biological functions such as immunomodulation, apoptosis, and anti-tumor activity. In this study, we investigated the effects of Korean mistletoe extract (KME) on lifespan in experimental models using Caenorhabditis elegans and Drosophila melanogaster. Supplementation of KME at 50 mu g/ml extended the mean survival time by 9.61 and 19.86 % in worms and flies, respectively. The longevity benefit of KME was not due to reduced feeding, reproduction, and/or locomotion in flies and worms. The supplementation of KME also did not increase resistance to various stresses including heat shock, oxidative, or starvation stresses. Furthermore, KME did not further extend the lifespan of flies fed a dietary restricted diet but did increase the expression of Sir2, one of the target genes of dietary restriction, suggesting that KME may function as a putative dietary restriction mimetic. These results also suggest that the longevity promoting effects of KME may be an example of mild stress-induced hormesis. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | BIOGERONTOLOGY | - |
dc.title | Korean mistletoe (Viscum album coloratum) extract extends the lifespan of nematodes and fruit flies | - |
dc.type | Article | - |
dc.contributor.college | 생명과학과 | - |
dc.identifier.doi | 10.1007/S10522-013-9487-7 | - |
dc.author.google | Lee, SH | - |
dc.author.google | An, HS | - |
dc.author.google | Jung, YW | - |
dc.author.google | Lee, EJ | - |
dc.author.google | Lee, HY | - |
dc.author.google | Choi, ES | - |
dc.author.google | An, SW | - |
dc.author.google | Son, H | - |
dc.author.google | Lee, SJ | - |
dc.author.google | Kim, JB | - |
dc.author.google | Min, KJ | - |
dc.relation.volume | 15 | - |
dc.relation.issue | 2 | - |
dc.relation.startpage | 153 | - |
dc.relation.lastpage | 164 | - |
dc.contributor.id | 10201212 | - |
dc.relation.journal | BIOGERONTOLOGY | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCIE | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOGERONTOLOGY, v.15, no.2, pp.153 - 164 | - |
dc.identifier.wosid | 000332454300004 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 164 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 153 | - |
dc.citation.title | BIOGERONTOLOGY | - |
dc.citation.volume | 15 | - |
dc.contributor.affiliatedAuthor | Lee, SJ | - |
dc.identifier.scopusid | 2-s2.0-84896390053 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 9 | - |
dc.description.scptc | 8 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CALORIE RESTRICTION | - |
dc.subject.keywordPlus | C. ELEGANS | - |
dc.subject.keywordPlus | RESVERATROL SUPPLEMENTATION | - |
dc.subject.keywordPlus | ANTIOXIDANT ACTIVITY | - |
dc.subject.keywordPlus | DIETARY RESTRICTION | - |
dc.subject.keywordPlus | STRESS RESISTANCE | - |
dc.subject.keywordPlus | IMPROVES HEALTH | - |
dc.subject.keywordPlus | STEM-CELLS | - |
dc.subject.keywordPlus | LECTIN | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordAuthor | Korean mistletoe extract | - |
dc.subject.keywordAuthor | Lifespan | - |
dc.subject.keywordAuthor | Dietary restriction | - |
dc.subject.keywordAuthor | Caenorhabditis elegans | - |
dc.subject.keywordAuthor | Drosophila melanogaster | - |
dc.relation.journalWebOfScienceCategory | Geriatrics & Gerontology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Geriatrics & Gerontology | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.