DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, C | - |
dc.contributor.author | Cho, EC | - |
dc.contributor.author | Chen, JY | - |
dc.contributor.author | Song, KH | - |
dc.contributor.author | Au, L | - |
dc.contributor.author | Favazza, C | - |
dc.contributor.author | Zhang, QA | - |
dc.contributor.author | Cobley, CM | - |
dc.contributor.author | Gao, F | - |
dc.contributor.author | Xia, YN | - |
dc.contributor.author | Wang, LHV | - |
dc.date.accessioned | 2016-03-31T08:29:02Z | - |
dc.date.available | 2016-03-31T08:29:02Z | - |
dc.date.created | 2013-07-31 | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 1936-0851 | - |
dc.identifier.other | 2010-OAK-0000027901 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/15408 | - |
dc.description.abstract | Early diagnosis, accurate staging, and image-guided resection of melanomas remain crucial clinical objectives for improving patient survival and treatment outcomes. Conventional techniques cannot meet this demand because of the low sensitivity, low specificity, poor spatial resolution, shallow penetration, and/or ionizing radiation. Here we overcome such limitations by combining high-resolution photoacoustic tomography (PAT) with extraordinarily optical absorbing gold nanocages (AuNCs). When bioconjugated with (Nle(4),D-Phe(7)]-alpha-melanocyte-stimulating hormone, the AuNCs can serve as a novel contrast agent for in vivo molecular PAT of melanomas with both exquisite sensitivity and high specificity. The bioconjugated AuNCs enhanced contrast similar to 300% more than the control, PEGylated AuNCs. The in vivo PAT quantification of the amount of AuNCs accumulated in melanomas was further validated with inductively coupled plasma mass spectrometry (ICP-MS). | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | American Chemical Society | - |
dc.relation.isPartOf | ACS NANO | - |
dc.subject | photoacoustic tomography | - |
dc.subject | gold nanocages | - |
dc.subject | melanoma | - |
dc.subject | bioconjugation | - |
dc.subject | molecular imaging | - |
dc.subject | POSITRON-EMISSION-TOMOGRAPHY | - |
dc.subject | NEAR-INFRARED LIGHT | - |
dc.subject | CARBON NANOTUBES | - |
dc.subject | CUTANEOUS MELANOMA | - |
dc.subject | MICROSCOPY | - |
dc.subject | ANGIOGENESIS | - |
dc.subject | RESOLUTION | - |
dc.subject | NANORODS | - |
dc.subject | HORMONE | - |
dc.subject | BRAIN | - |
dc.title | In Vivo Molecular Photoacoustic Tomography of Melanomas Targeted by Bioconjugated Gold Nanocages | - |
dc.type | Article | - |
dc.contributor.college | 전자전기공학과 | - |
dc.identifier.doi | 10.1021/nn100736c | - |
dc.author.google | Kim, C | - |
dc.author.google | Cho, EC | - |
dc.author.google | Chen, JY | - |
dc.author.google | Song, KH | - |
dc.author.google | Au, L | - |
dc.author.google | Favazza, C | - |
dc.author.google | Zhang, QA | - |
dc.author.google | Cobley, CM | - |
dc.author.google | Gao, F | - |
dc.author.google | Xia, YN | - |
dc.author.google | Wang, LHV | - |
dc.relation.volume | 4 | - |
dc.relation.issue | 8 | - |
dc.relation.startpage | 4559 | - |
dc.relation.lastpage | 4564 | - |
dc.contributor.id | 11117022 | - |
dc.relation.journal | ACS NANO | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | ACS NANO, v.4, no.8, pp.4559 - 4564 | - |
dc.identifier.wosid | 000281052700028 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 4564 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 4559 | - |
dc.citation.title | ACS NANO | - |
dc.citation.volume | 4 | - |
dc.contributor.affiliatedAuthor | Kim, C | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 288 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CARBON NANOTUBES | - |
dc.subject.keywordPlus | MICROSCOPY | - |
dc.subject.keywordPlus | ANGIOGENESIS | - |
dc.subject.keywordPlus | RESOLUTION | - |
dc.subject.keywordPlus | HORMONE | - |
dc.subject.keywordAuthor | photoacoustic tomography | - |
dc.subject.keywordAuthor | gold nanocages | - |
dc.subject.keywordAuthor | melanoma | - |
dc.subject.keywordAuthor | bioconjugation | - |
dc.subject.keywordAuthor | molecular imaging | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
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