Tissue specific delivery of estrone-conjugated siRNAs
SCIE
SCOPUS
- Title
- Tissue specific delivery of estrone-conjugated siRNAs
- Authors
- Bang, EK; Jeon, EM; Wanil Kim; Kyung-Ha Lee; Kim, KT; Kim, BH
- Date Issued
- 2013-05
- Publisher
- RSC Publishing
- Abstract
- An estrone phosphoramidite, synthesized in a single step, was directly incorporated at the 5' ends of small interfering RNAs (siRNAs). The resulting estrone-conjugated siRNAs readily pass through cellular membranes and down-regulate the target protein, and show specific distributions in vivo.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/15643
- DOI
- 10.1039/C2MB25258A
- ISSN
- 1742-206X
- Article Type
- Article
- Citation
- Molecular BioSystems, vol. 9, no. 5, page. 974 - 977, 2013-05
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