An efficient and practical method for the synthesis of mono-N-protected alpha,omega-diaminoalkanes
SCIE
SCOPUS
- Title
- An efficient and practical method for the synthesis of mono-N-protected alpha,omega-diaminoalkanes
- Authors
- Lee, JW; Jun, SI; Kim, K
- Date Issued
- 2001-04-02
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- The large-scale synthesis of mono-N-protected (Cbz, Boc, Ts, and Ns) alpha,omega -diaminoalkanes (the number of carbon atoms = 3, 4, 5 and 6) are accomplished in 81-945 yield by the protection of amine and subsequent reduction of an azido group from alpha,omega -azido alkyl amines. alpha,omega -Azido alkyl amines are prepared efficiently by the partial reduction of alpha,omega -diazidoalkanes which are obtained from the corresponding dibromoalkanes. (C) 2001 Elsevier Science Ltd. All rights reserved.
- Keywords
- mono-protection; alpha,omega-diaminoalkanes; azides; reduction; MOLECULAR NECKLACE; POLYAMINE; CUCURBITURIL; POLYROTAXANE; ROTAXANE; SPERMINE; DNA
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/19613
- DOI
- 10.1016/S0040-4039(01)00282-9
- ISSN
- 0040-4039
- Article Type
- Article
- Citation
- TETRAHEDRON LETTERS, vol. 42, no. 14, page. 2709 - 2711, 2001-04-02
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- There are no files associated with this item.
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