Reinforcing Polycaprolactone (PCL) nanofiber with a recombinant mussel adhesive protein-1 (Rmfp-1)
- Title
- Reinforcing Polycaprolactone (PCL) nanofiber with a recombinant mussel adhesive protein-1 (Rmfp-1)
- Authors
- 김상식
- Date Issued
- 2013
- Publisher
- 포항공과대학교
- Abstract
- Electrospun Poly (ε-caprolactone) (PCL) nanofibers have been widely used for tissue engineering applications. However, the poor mechanical properties of PCL nanofibers limit their further utilization in hard tissue engineering. To improve the mechanical properties of PCL nanofibers, we fabricated nanofiber mats by blending PCL and recombinant mussel coating protein (Rmfp-1) to mimic the protective coating of mussels (Mytilus species) which is hard (~comparable to epoxy resin) yet flexible(ε~>70%). The stiffness of PCL/Rmfp-1 nanofiber mat increases linearly with the concentration of DOPA-Fe3+ complex which is a key component of the mussel protective coating in mfp-1. Mimicking the mussel protective coating is a new strategy to enhance the mechanical properties of biomedical materials
- URI
- http://postech.dcollection.net/jsp/common/DcLoOrgPer.jsp?sItemId=000001627736
https://oasis.postech.ac.kr/handle/2014.oak/2003
- Article Type
- Thesis
- Files in This Item:
- There are no files associated with this item.
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