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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ahn, KH | - |
| dc.contributor.author | Lee, SJ | - |
| dc.contributor.author | Lee, CH | - |
| dc.contributor.author | Hong, CY | - |
| dc.contributor.author | Park, TK | - |
| dc.date.accessioned | 2016-03-31T13:41:53Z | - |
| dc.date.available | 2016-03-31T13:41:53Z | - |
| dc.date.created | 2009-08-07 | - |
| dc.date.issued | 1999-05-17 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.other | 1999-OAK-0000000748 | - |
| dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/20405 | - |
| dc.description.abstract | 3-Arylpyrrolidines are synthesized through the coupling of N-benzyl-3-(methanesulfonyloxy)pyrrolidine with diarylcuprates. Pharmacological evaluation of a series of N-substituted-3-arylpyrrolidines toward several neurotransmitter receptors indicated that some of them are good ligands for serotonin 1A receptor. Particularly, N-[(N-saccharino)butyl]pyrrolidines were found to be potent and selective ligands. A preliminary biological evaluation for several selected compounds indicated that they are potentially effective antianxiety and antidepressant agents. (C) 1999 Elsevier Science Ltd. All rights reserved. | - |
| dc.description.statementofresponsibility | X | - |
| dc.language | English | - |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
| dc.relation.isPartOf | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.subject | ENANTIOSELECTIVE SYNTHESIS | - |
| dc.subject | ANTIDEPRESSANT | - |
| dc.subject | PYRROLIDINES | - |
| dc.subject | ABT-200 | - |
| dc.subject | AGENTS | - |
| dc.title | N-substituted-3-arylpyrrolidines: Potent and selective ligands at serotonin 1A receptor | - |
| dc.type | Article | - |
| dc.contributor.college | 분자소재융합계의 전자-광 거동연구센터 | - |
| dc.identifier.doi | 10.1016/S0960-894X(99)00201-2 | - |
| dc.author.google | Ahn, KH | - |
| dc.author.google | Lee, SJ | - |
| dc.author.google | Lee, CH | - |
| dc.author.google | Hong, CY | - |
| dc.author.google | Park, TK | - |
| dc.relation.volume | 9 | - |
| dc.relation.issue | 10 | - |
| dc.relation.startpage | 1379 | - |
| dc.relation.lastpage | 1384 | - |
| dc.contributor.id | 10087916 | - |
| dc.relation.journal | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.relation.index | SCI급, SCOPUS 등재논문 | - |
| dc.relation.sci | SCI | - |
| dc.collections.name | Journal Papers | - |
| dc.type.rims | ART | - |
| dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.9, no.10, pp.1379 - 1384 | - |
| dc.identifier.wosid | 000080454300009 | - |
| dc.date.tcdate | 2019-01-01 | - |
| dc.citation.endPage | 1384 | - |
| dc.citation.number | 10 | - |
| dc.citation.startPage | 1379 | - |
| dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.volume | 9 | - |
| dc.contributor.affiliatedAuthor | Ahn, KH | - |
| dc.identifier.scopusid | 2-s2.0-0033577775 | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalClass | 1 | - |
| dc.description.wostc | 17 | - |
| dc.type.docType | Article | - |
| dc.subject.keywordPlus | ENANTIOSELECTIVE SYNTHESIS | - |
| dc.subject.keywordPlus | ANTIDEPRESSANT | - |
| dc.subject.keywordPlus | PYRROLIDINES | - |
| dc.subject.keywordPlus | ABT-200 | - |
| dc.subject.keywordPlus | AGENTS | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Chemistry | - |
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Related Researcher
- 안교한AHN, KYO HAN
- Dept of Chemistry