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Cited 30 time in webofscience Cited 30 time in scopus
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dc.contributor.authorChung, SK-
dc.contributor.authorRyoo, CH-
dc.contributor.authorYang, HW-
dc.contributor.authorShim, JY-
dc.contributor.authorKang, MG-
dc.contributor.authorLee, KW-
dc.contributor.authorKang, HI-
dc.date.accessioned2016-03-31T13:46:57Z-
dc.date.available2016-03-31T13:46:57Z-
dc.date.created2009-02-28-
dc.date.issued1998-12-24-
dc.identifier.issn0040-4020-
dc.identifier.other1998-OAK-0000000511-
dc.identifier.urihttps://oasis.postech.ac.kr/handle/2014.oak/20575-
dc.description.abstractA series of lanosterol and cholesterol derivatives with modified side chain structures, which might interfere with sterol C24-methyltransferase in the ergosterol biosynthesis as substrate analogs, have been synthesized. The in vitro bioassay studies have shown that some of these compounds, in particular with C24-amino- and thio-functionalities, possess potent antifungal activities. in vivo. Bioassays have also been carried out for the leading compounds. (C) 1998 Elsevier Science Ltd. All rights reserved.-
dc.description.statementofresponsibilityX-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.relation.isPartOfTETRAHEDRON-
dc.subjectDELTA-24-STEROL METHYLTRANSFERASE-
dc.subjectSACCHAROMYCES-CEREVISIAE-
dc.subjectENZYME INACTIVATORS-
dc.subjectMETHYL TRANSFERASE-
dc.subjectCANDIDA-ALBICANS-
dc.subjectMECHANISM-
dc.subjectBIOSYNTHESIS-
dc.subjectINHIBITORS-
dc.subjectCATALYSIS-
dc.titleSynthesis and bioactivities of steroid derivatives as antifungal agents-
dc.typeArticle-
dc.contributor.college화학과-
dc.identifier.doi10.1016/S0040-4020(98)01000-X-
dc.author.googleCHUNG, SK-
dc.author.googleRYOO, CH-
dc.author.googleYANG, HW-
dc.author.googleSHIM, JY-
dc.author.googleKANG, MG-
dc.author.googleLEE, KW-
dc.author.googleKANG, HI-
dc.relation.volume54-
dc.relation.issue52-
dc.relation.startpage15899-
dc.relation.lastpage15914-
dc.contributor.id10200284-
dc.relation.journalTETRAHEDRON-
dc.relation.indexSCI급, SCOPUS 등재논문-
dc.relation.sciSCI-
dc.collections.nameJournal Papers-
dc.type.rimsART-
dc.identifier.bibliographicCitationTETRAHEDRON, v.54, no.52, pp.15899 - 15914-
dc.identifier.wosid000077432500013-
dc.date.tcdate2019-01-01-
dc.citation.endPage15914-
dc.citation.number52-
dc.citation.startPage15899-
dc.citation.titleTETRAHEDRON-
dc.citation.volume54-
dc.contributor.affiliatedAuthorChung, SK-
dc.identifier.scopusid2-s2.0-0032564534-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.wostc27-
dc.type.docTypeArticle-
dc.subject.keywordPlusDELTA-24-STEROL METHYLTRANSFERASE-
dc.subject.keywordPlusSACCHAROMYCES-CEREVISIAE-
dc.subject.keywordPlusENZYME INACTIVATORS-
dc.subject.keywordPlusMETHYL TRANSFERASE-
dc.subject.keywordPlusCANDIDA-ALBICANS-
dc.subject.keywordPlusMECHANISM-
dc.subject.keywordPlusBIOSYNTHESIS-
dc.subject.keywordPlusINHIBITORS-
dc.subject.keywordPlusCATALYSIS-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-

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