DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, SY | - |
dc.contributor.author | Lee, MS | - |
dc.contributor.author | Lee, HY | - |
dc.contributor.author | Kim, SD | - |
dc.contributor.author | Shim, JW | - |
dc.contributor.author | Jo, SH | - |
dc.contributor.author | Lee, JW | - |
dc.contributor.author | Kim, JY | - |
dc.contributor.author | Choi, YW | - |
dc.contributor.author | Baek, SH | - |
dc.contributor.author | Ryu, SH | - |
dc.contributor.author | Bae, YS | - |
dc.date.accessioned | 2016-04-01T01:17:36Z | - |
dc.date.available | 2016-04-01T01:17:36Z | - |
dc.date.created | 2009-08-13 | - |
dc.date.issued | 2008-01 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.other | 2008-OAK-0000007906 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/22670 | - |
dc.description.abstract | F2L, a peptide derived from heme-binding protein, was originally identified as an endogenous ligand for formyl peptide receptor-like (FPRL)2. Previously, we reported that F2L inhibits FPR and FPRL1-mediated signaling in neutrophils. Since endothelial cells express functional FPRL1, we examined the effect of F2L on LL-37 (an FPRL1 agonist)-induced signaling in human umbilical vein endothelial cells (HUVECs). F2L stimulated the chemotactic migration in HUVECs. However, F2L inhibited FPRL1 activity, resulting in the inhibition of cell proliferation and tube formation induced by LL-37 in HUVECs. We suggest that F2L will potentially be useful in the study of FPRL1 signaling and the development of drugs to treat diseases involving the FPRL1 in the vascular system. (C) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.relation.isPartOf | FEBS LETTERS | - |
dc.subject | F2L | - |
dc.subject | formyl peptide receptor-like 1 | - |
dc.subject | chemotaxis | - |
dc.subject | angiogenesis | - |
dc.subject | cell proliferation | - |
dc.subject | endothelial cell | - |
dc.subject | SPHINGOSINE 1-PHOSPHATE | - |
dc.subject | NATURAL ANTAGONIST | - |
dc.subject | LYSOPHOSPHATIDIC ACID | - |
dc.subject | HUMAN MONOCYTES | - |
dc.subject | IN-VITRO | - |
dc.subject | ANGIOGENESIS | - |
dc.subject | RECEPTORS | - |
dc.subject | IDENTIFICATION | - |
dc.subject | LL-37 | - |
dc.subject | INVOLVEMENT | - |
dc.title | F2L, a peptide derived from heme-binding protein, inhibits LL-37-induced cell proliferation and tube formation in human umbilical vein endothelial cells | - |
dc.type | Article | - |
dc.contributor.college | 생명과학과 | - |
dc.identifier.doi | 10.1016/j.febslet.2007.12.015 | - |
dc.author.google | Lee, SY | - |
dc.author.google | Lee, MS | - |
dc.author.google | Lee, HY | - |
dc.author.google | Kim, SD | - |
dc.author.google | Shim, JW | - |
dc.author.google | Jo, SH | - |
dc.author.google | Lee, JW | - |
dc.author.google | Kim, JY | - |
dc.author.google | Choi, YW | - |
dc.author.google | Baek, SH | - |
dc.author.google | Ryu, SH | - |
dc.author.google | Bae, YS | - |
dc.relation.volume | 582 | - |
dc.relation.issue | 2 | - |
dc.relation.startpage | 273 | - |
dc.relation.lastpage | 278 | - |
dc.contributor.id | 10069853 | - |
dc.relation.journal | FEBS LETTERS | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | FEBS LETTERS, v.582, no.2, pp.273 - 278 | - |
dc.identifier.wosid | 000257271700022 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 278 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 273 | - |
dc.citation.title | FEBS LETTERS | - |
dc.citation.volume | 582 | - |
dc.contributor.affiliatedAuthor | Ryu, SH | - |
dc.identifier.scopusid | 2-s2.0-38049079769 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 13 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | SPHINGOSINE 1-PHOSPHATE | - |
dc.subject.keywordPlus | NATURAL ANTAGONIST | - |
dc.subject.keywordPlus | LYSOPHOSPHATIDIC ACID | - |
dc.subject.keywordPlus | HUMAN MONOCYTES | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | ANGIOGENESIS | - |
dc.subject.keywordPlus | RECEPTORS | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | LL-37 | - |
dc.subject.keywordPlus | INVOLVEMENT | - |
dc.subject.keywordAuthor | F2L | - |
dc.subject.keywordAuthor | formyl peptide receptor-like 1 | - |
dc.subject.keywordAuthor | chemotaxis | - |
dc.subject.keywordAuthor | angiogenesis | - |
dc.subject.keywordAuthor | cell proliferation | - |
dc.subject.keywordAuthor | endothelial cell | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalResearchArea | Cell Biology | - |
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