DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, YK | - |
dc.contributor.author | Kim, S | - |
dc.contributor.author | Lim, G | - |
dc.contributor.author | Granick, S | - |
dc.date.accessioned | 2016-04-01T02:37:58Z | - |
dc.date.available | 2016-04-01T02:37:58Z | - |
dc.date.created | 2010-12-02 | - |
dc.date.issued | 2001-12-11 | - |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.other | 2001-OAK-0000022163 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/25487 | - |
dc.description.abstract | We report the first use of a surface forces apparatus to study the hybridization of DNA. We study the regime of very high ionic strength (approximate to1 M) at which commercial DNA chip operations are performed. Using a thiol end-attached single-stranded oligonucleotide, we find that exposure to the complementary strand resulted in larger thickness. In addition, the resistance to small-amplitude shear deformations when opposed to a nonadsorbing surface (mica) increased significantly after hybridization. The thickness at onset of significant shear resistance was, for single-stranded DNA, considerably less than that of hybridized DNA. This could provide a new method to detect DNA hybridization efficiency. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.relation.isPartOf | LANGMUIR | - |
dc.subject | MONOLAYERS | - |
dc.subject | GOLD | - |
dc.title | A Surface Forces Study of DNA Hybridization | - |
dc.type | Article | - |
dc.contributor.college | 융합생명공학부 | - |
dc.identifier.doi | 10.1021/la0113769 | - |
dc.author.google | Cho, YK | - |
dc.author.google | Kim, S | - |
dc.author.google | Lim, G | - |
dc.author.google | Granick, S | - |
dc.relation.volume | 17 | - |
dc.relation.issue | 25 | - |
dc.relation.startpage | 7732 | - |
dc.relation.lastpage | 7734 | - |
dc.contributor.id | 10097203 | - |
dc.relation.journal | LANGMUIR | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | LANGMUIR, v.17, no.25, pp.7732 - 7734 | - |
dc.identifier.wosid | 000172590800006 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 7734 | - |
dc.citation.number | 25 | - |
dc.citation.startPage | 7732 | - |
dc.citation.title | LANGMUIR | - |
dc.citation.volume | 17 | - |
dc.contributor.affiliatedAuthor | Lim, G | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 25 | - |
dc.type.docType | Letter | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
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