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TLRs bent into shape SCIE SCOPUS
- Title
- TLRs bent into shape
- Authors
- Kim, YM; Brinkmann, MM; Ploegh, HL
- Date Issued
- 2007-07
- Publisher
- NATURE PUBLISHING GROUP
- Abstract
- Toll-like receptors respond to ligands embedded in pathogen-derived macromolecules to induce immune responses. Binding of a stimulatory ligand to preexisting dimers of Toll-like receptor 9 induces conformational changes that lead to their full activation.
- Keywords
- TOLL-LIKE RECEPTOR-3; CPG-DNA; BINDING; SIGNALS; ER
- ISSN
- 1529-2908
- Article Type
- Article
- Citation
- NATURE IMMUNOLOGY, vol. 8, no. 7, page. 674 - 676, 2007-07
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