DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, C | - |
dc.contributor.author | Bin Baek, S | - |
dc.contributor.author | Kim, DH | - |
dc.contributor.author | Lim, SC | - |
dc.contributor.author | Lee, HJ | - |
dc.contributor.author | Lee, HC | - |
dc.date.accessioned | 2016-04-01T03:12:16Z | - |
dc.date.available | 2016-04-01T03:12:16Z | - |
dc.date.created | 2010-04-14 | - |
dc.date.issued | 2009-05 | - |
dc.identifier.issn | 1075-2617 | - |
dc.identifier.other | 2009-OAK-0000020524 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/26385 | - |
dc.description.abstract | The temperature dependence of the partition of a neuropeptide, substance P(SP), in isotropic (q = 0.5)bicelles was investigated by using pulsed field gradient NMR diffusion technique. The partition coefficient decreases as the temperature is increased from 295 to 325 K, indicating a favorable (negative) enthalpy change upon partitioning of the peptide. Thermodynamic analysis of the data shows that the partitioning of SIR at 300 K is driven by the enthalpic term (Delta H) with the value of -4.03 kcal mol(-1), while it is opposed by the entropic term (-T Delta S) by approximately 1.28 kcal mol(-1) with a small negative change in heat capacity (Delta C-p). The enthalpy-driven process for the partition of SIR in bicelles is the same as in dodecylphosphocholine (DPC) micelles, however, the negative entropy change in bicelles of flat bilayer surface is in sharp contrast with the positive entropy change in DPC micelles of highly curved surface, indicating that the curvature of the membrane surface might play a significant role in the partitioning of peptides. Copyright (C) 2009 European Peptide Society and John Wiley & Sons, Ltd. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | JOHN WILEY & SONS LTD | - |
dc.relation.isPartOf | JOURNAL OF PEPTIDE SCIENCE | - |
dc.subject | substance P | - |
dc.subject | isotropic bicelle | - |
dc.subject | PFG NMR | - |
dc.subject | partitioning | - |
dc.subject | partition coefficient | - |
dc.subject | diffusion coefficient | - |
dc.subject | NMR SOLUTION STRUCTURE | - |
dc.subject | FAST-TUMBLING BICELLES | - |
dc.subject | TEMPERATURE-DEPENDENCE | - |
dc.subject | PHOSPHOLIPID BICELLES | - |
dc.subject | TRANSLATIONAL DIFFUSION | - |
dc.subject | MEMBRANE INTERACTION | - |
dc.subject | BINDING | - |
dc.subject | CONFORMATION | - |
dc.subject | PEPTIDES | - |
dc.subject | MICELLES | - |
dc.title | Thermodynamics of partitioning of substance P in isotropic bicelles | - |
dc.type | Article | - |
dc.contributor.college | 화학과 | - |
dc.identifier.doi | 10.1002/PSC.1121 | - |
dc.author.google | Kim, C | - |
dc.author.google | Bin Baek, S | - |
dc.author.google | Kim, DH | - |
dc.author.google | Lim, SC | - |
dc.author.google | Lee, HJ | - |
dc.author.google | Lee, HC | - |
dc.relation.volume | 15 | - |
dc.relation.issue | 5 | - |
dc.relation.startpage | 353 | - |
dc.relation.lastpage | 358 | - |
dc.contributor.id | 10110630 | - |
dc.relation.journal | JOURNAL OF PEPTIDE SCIENCE | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | JOURNAL OF PEPTIDE SCIENCE, v.15, no.5, pp.353 - 358 | - |
dc.identifier.wosid | 000265419700004 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 358 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 353 | - |
dc.citation.title | JOURNAL OF PEPTIDE SCIENCE | - |
dc.citation.volume | 15 | - |
dc.contributor.affiliatedAuthor | Lee, HC | - |
dc.identifier.scopusid | 2-s2.0-67649209049 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 7 | - |
dc.description.scptc | 5 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | NMR SOLUTION STRUCTURE | - |
dc.subject.keywordPlus | FAST-TUMBLING BICELLES | - |
dc.subject.keywordPlus | TEMPERATURE-DEPENDENCE | - |
dc.subject.keywordPlus | PHOSPHOLIPID BICELLES | - |
dc.subject.keywordPlus | TRANSLATIONAL DIFFUSION | - |
dc.subject.keywordPlus | MEMBRANE INTERACTION | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | CONFORMATION | - |
dc.subject.keywordPlus | PEPTIDES | - |
dc.subject.keywordPlus | MICELLES | - |
dc.subject.keywordAuthor | substance P | - |
dc.subject.keywordAuthor | isotropic bicelle | - |
dc.subject.keywordAuthor | PFG NMR | - |
dc.subject.keywordAuthor | partitioning | - |
dc.subject.keywordAuthor | partition coefficient | - |
dc.subject.keywordAuthor | diffusion coefficient | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
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