DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, HS | - |
dc.contributor.author | Kim, KS | - |
dc.contributor.author | Kim, CJ | - |
dc.contributor.author | Hahn, SK | - |
dc.contributor.author | Jo, MH | - |
dc.date.accessioned | 2016-04-01T08:39:45Z | - |
dc.date.available | 2016-04-01T08:39:45Z | - |
dc.date.created | 2009-04-15 | - |
dc.date.issued | 2009-02-15 | - |
dc.identifier.issn | 0956-5663 | - |
dc.identifier.other | 2009-OAK-0000017994 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/28483 | - |
dc.description.abstract | We report the real-time, label-free and electrical detection of vascular endotherial growth factor (VEGF) for cancer diagnosis using anti-VEGF aptamer-modified Si nanowire field-effect transistors (SiNW-FETs). Specifically, the high quality single-crystalline SiNWs of both n-type and p-type characters were surface modified with the covalent immobilization of anti-VEGF aptamers, and they were turned into SiNW-FET biosensors for the VEGF detection. We show that the VEGF molecules consistently act on the gate dielectrics of both n-type and p-type SiNW-FETs as electrically positive point-charges; their recognition to anti-VEGF aptamers depletes (accumulates) the charge carriers in the p-type (n-type) SiNW-FETs and thus decreases (increases) the detection currents. The detection limit for VEGFs in this study was determined as 1.04 nM and 104 pM for the cases of n-type and p-type SiNW-FETs, respectively. (C) 2008 Elsevier B.V. All rights reserved. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | ELSEVIER ADVANCED TECHNOLOGY | - |
dc.relation.isPartOf | BIOSENSORS & BIOELECTRONICS | - |
dc.title | Electrical detection of VEGFs for cancer diagnoses using anti-vascular endotherial growth factor aptamer-modified Si nanowire FETs | - |
dc.type | Article | - |
dc.contributor.college | 신소재공학과 | - |
dc.identifier.doi | 10.1016/J.BIOS.2008.08.036 | - |
dc.author.google | Lee, HS | - |
dc.author.google | Kim, KS | - |
dc.author.google | Kim, CJ | - |
dc.author.google | Hahn, SK | - |
dc.author.google | Jo, MH | - |
dc.relation.volume | 24 | - |
dc.relation.issue | 6 | - |
dc.relation.startpage | 1801 | - |
dc.relation.lastpage | 1805 | - |
dc.contributor.id | 10176415 | - |
dc.relation.journal | BIOSENSORS & BIOELECTRONICS | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOSENSORS & BIOELECTRONICS, v.24, no.6, pp.1801 - 1805 | - |
dc.identifier.wosid | 000263778000044 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 1805 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1801 | - |
dc.citation.title | BIOSENSORS & BIOELECTRONICS | - |
dc.citation.volume | 24 | - |
dc.contributor.affiliatedAuthor | Kim, CJ | - |
dc.contributor.affiliatedAuthor | Hahn, SK | - |
dc.contributor.affiliatedAuthor | Jo, MH | - |
dc.identifier.scopusid | 2-s2.0-67649168061 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 96 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Aptamer sensors | - |
dc.subject.keywordAuthor | Si nanowire field-effect transistor | - |
dc.subject.keywordAuthor | RNA aptamer | - |
dc.subject.keywordAuthor | Vascular endotherial growth factor | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
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