DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, J | - |
dc.contributor.author | Park, K | - |
dc.contributor.author | Hahn, SK | - |
dc.date.accessioned | 2016-04-01T09:07:38Z | - |
dc.date.available | 2016-04-01T09:07:38Z | - |
dc.date.created | 2009-03-05 | - |
dc.date.issued | 2008-01-01 | - |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.other | 2008-OAK-0000010792 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/29502 | - |
dc.description.abstract | The morphological analysis of novel quantum dot-hyaluronic acid (QDot-HA) conjugates was carried outwith a transmission electron microscope (TEM). Adipic acid dihydrazide-modified HA (HA-ADH) was synthesized and conjugated to quantum dots (QDots) having carboxyl terminal ligands which were activated with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) and N-hydroxysulfosuccinimide (sulfo-NHS). HA molecules with a molecular weight (MW) of 20 K, 234 K and 3000 K were used to investigate the effect of MW on the morphology of QDot-HA conjugates. The TEM micrographs of QDot-HA conjugates showed branched and multi-layered chain type morphology formed by inter- and intra-molecular conjugation of QDots to HA molecules. The size of QDot-HA conjugate increased with the MW of HA. QDot-HA conjugate could be successfully used for real-time bio-imaging of HA derivatives in nude mice. The novel QDot-HA conjugate will be further used to investigate the biological roles of HA with a different MW in the body. (c) 2007 Published by Elsevier B.V. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.subject | quantum dots | - |
dc.subject | hyaluronic acid | - |
dc.subject | conjugates | - |
dc.subject | TEM images | - |
dc.subject | bio-imaging | - |
dc.subject | SUSTAINED-RELEASE FORMULATION | - |
dc.subject | IN-VIVO | - |
dc.subject | CELLS | - |
dc.subject | OLIGOSACCHARIDES | - |
dc.subject | NANOPARTICLES | - |
dc.subject | ENCAPSULATION | - |
dc.subject | HYDROGELS | - |
dc.subject | DELIVERY | - |
dc.title | Effect of hyaluronic acid molecular weight on the morphology of quantum dot-hyaluronic acid conjugates | - |
dc.type | Article | - |
dc.contributor.college | 신소재공학과 | - |
dc.identifier.doi | 10.1016/j.ijbiomac.2007.09.002 | - |
dc.author.google | Kim, J | - |
dc.author.google | Park, K | - |
dc.author.google | Hahn, SK | - |
dc.relation.volume | 42 | - |
dc.relation.issue | 1 | - |
dc.relation.startpage | 41 | - |
dc.relation.lastpage | 45 | - |
dc.contributor.id | 10149037 | - |
dc.relation.journal | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, v.42, no.1, pp.41 - 45 | - |
dc.identifier.wosid | 000252624900008 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 45 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 41 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.citation.volume | 42 | - |
dc.contributor.affiliatedAuthor | Hahn, SK | - |
dc.identifier.scopusid | 2-s2.0-36549046106 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 26 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | SUSTAINED-RELEASE FORMULATION | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | ENCAPSULATION | - |
dc.subject.keywordPlus | DELIVERY | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordAuthor | quantum dots | - |
dc.subject.keywordAuthor | hyaluronic acid | - |
dc.subject.keywordAuthor | conjugates | - |
dc.subject.keywordAuthor | TEM images | - |
dc.subject.keywordAuthor | bio-imaging | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
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