DC Field | Value | Language |
---|---|---|
dc.contributor.author | You, KM | - |
dc.contributor.author | Lee, SH | - |
dc.contributor.author | Im, A | - |
dc.contributor.author | Lee, SB | - |
dc.date.accessioned | 2016-04-01T09:16:34Z | - |
dc.date.available | 2016-04-01T09:16:34Z | - |
dc.date.created | 2009-03-20 | - |
dc.date.issued | 2003-03 | - |
dc.identifier.issn | 1226-8372 | - |
dc.identifier.other | 2004-OAK-0000010432 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/29780 | - |
dc.description.abstract | Aptamers are functional nucleic acids that can specially bind to proteins, peptides, amino acids, nucleotides, drugs, vitamins and other organic and inorganic compounds. The aptamers are identified from random DNA or RNA libraries by a SELEX (systematic evolution of ligands by exponential amplification) process. As aptamers have the advantage, and potential ability to be released from the limitations of antibodies, they are attractive to a wide range of therapeutic and diagnostic applications. Aptamers, with a high-affinity and specificity, could fulfil molecular the recognition needs of various fields in biotechnology. in this work, we reviewed some aptamer selection techniques, properties, medical applications of their molecules and their biotechnological applications, such as ELONA (enzyme linked oligonucleotide assay), flow cytometry, biosensors, electrophoresis, chromatography and microarrays. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | KOREAN SOC BIOTECHNOLOGY & BIOENGINEE | - |
dc.relation.isPartOf | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | - |
dc.subject | aptamer | - |
dc.subject | SELEX | - |
dc.subject | ELONA | - |
dc.subject | flow cytometry | - |
dc.subject | biosensor | - |
dc.subject | chromatography | - |
dc.subject | microarray | - |
dc.subject | SINGLE-STRANDED-DNA | - |
dc.subject | RNA APTAMERS | - |
dc.subject | GROWTH-FACTOR | - |
dc.subject | BINDING RNA | - |
dc.subject | TRANSSPLICING RIBOZYMES | - |
dc.subject | OLIGONUCLEOTIDE LIGANDS | - |
dc.subject | AFFINITY-CHROMATOGRAPHY | - |
dc.subject | COMBINATORIAL LIBRARIES | - |
dc.subject | STATIONARY-PHASE/ | - |
dc.subject | RECEPTOR-BINDING | - |
dc.title | Aptamers as functional nucleic acids: In vitro selection and biotechnological applications | - |
dc.type | Article | - |
dc.contributor.college | 경북씨그랜트센터 | - |
dc.identifier.doi | 10.1007/BF02940259 | - |
dc.author.google | You, KM | - |
dc.author.google | Lee, SH | - |
dc.author.google | Im, A | - |
dc.author.google | Lee, SB | - |
dc.relation.volume | 8 | - |
dc.relation.issue | 2 | - |
dc.relation.startpage | 64 | - |
dc.relation.lastpage | 75 | - |
dc.contributor.id | 10105619 | - |
dc.relation.journal | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.8, no.2, pp.64 - 75 | - |
dc.identifier.wosid | 000188831000003 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 75 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 64 | - |
dc.citation.title | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | - |
dc.citation.volume | 8 | - |
dc.contributor.affiliatedAuthor | Lee, SB | - |
dc.identifier.scopusid | 2-s2.0-346235036 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 60 | - |
dc.type.docType | Review | - |
dc.subject.keywordPlus | STRANDED-DNA MOLECULES | - |
dc.subject.keywordPlus | RNA APTAMERS | - |
dc.subject.keywordPlus | BINDING RNA | - |
dc.subject.keywordPlus | AFFINITY-CHROMATOGRAPHY | - |
dc.subject.keywordPlus | COMBINATORIAL CHEMISTRY | - |
dc.subject.keywordPlus | OLIGONUCLEOTIDE LIGANDS | - |
dc.subject.keywordPlus | INHIBIT | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | RECOGNITION | - |
dc.subject.keywordPlus | EVOLUTION | - |
dc.subject.keywordAuthor | aptamer | - |
dc.subject.keywordAuthor | SELEX | - |
dc.subject.keywordAuthor | ELONA | - |
dc.subject.keywordAuthor | flow cytometry | - |
dc.subject.keywordAuthor | biosensor | - |
dc.subject.keywordAuthor | chromatography | - |
dc.subject.keywordAuthor | microarray | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
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