Physically microstriped-nanoengineered polystyrene surface (PMS-NPS) for regulating cell attachment and alignment fabricated by nano-injection molding
SCIE
SCOPUS
- Title
- Physically microstriped-nanoengineered polystyrene surface (PMS-NPS) for regulating cell attachment and alignment fabricated by nano-injection molding
- Authors
- Kyoung Je Cha; Jiwon Lim; Moon-Hee Na; Kim, DS
- Date Issued
- 2016-06-01
- Publisher
- ELSEVIER SCIENCE
- Abstract
- In the present study, we developed a physically microstriped-nanoengineered polystyrene surface (PMS-NPS) to control cell attachment and alignment. The PMS-NPS was mass replicated by nano-injection molding with a rigid metallic nano-mold insert, which was cost-effectively manufactured by two-step anodization process, UV-photolithography, and electroforming process. In our previous result, attachment of MG-63 cells was found to be enhanced on the nanoengineered polystyrene surface (NPS) without any biochemical treatments. In this study, the PMS-NPS was proposed to control the cell attachment and alignment by biophysical cue without biochemical cue. Throughout this study, we were able to observe the enhanced MG-63 cell attachment and alignment on PMS-NPS compared to flat PS. (C) 2016 Elsevier B.V. All rights reserved.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/36434
- DOI
- 10.1016/J.MEE.2016.02.034
- ISSN
- 0167-9317
- Article Type
- Article
- Citation
- MICROELECTRONIC ENGINEERING, vol. 158, no. 1, page. 11 - 15, 2016-06-01
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