G-quadruplex formation using fluorescent oligonucleotides as a detection method for discriminating AGG trinucleotide repeats
SCIE
SCOPUS
- Title
- G-quadruplex formation using fluorescent oligonucleotides as a detection method for discriminating AGG trinucleotide repeats
- Authors
- Park, Y; Kim, KT; Kim, BH
- Date Issued
- 2016-10
- Publisher
- Royal Society of Chemistry
- Abstract
- We have developed a simple and sensitive system for detecting AGG trinucleotide repeats through the formation of intermolecular G-quadruplexes using a fluorescent oligonucleotide. The fluorescence signal increased rapidly and dramatically by 44.7-fold with respect to the low background signal in the presence of RNA agg repeats and by 35.0-fold in the presence of DNA AGG repeats.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/37161
- DOI
- 10.1039/C6CC06566J
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- Chemical Communications, vol. 52, no. 86, page. 12757 - 12760, 2016-10
- Files in This Item:
-
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.