DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Kyeng Min | - |
dc.contributor.author | Baek, Kangkyun | - |
dc.contributor.author | Ko, Young Ho | - |
dc.contributor.author | Shrinidhi, Annadka | - |
dc.contributor.author | Murray, James | - |
dc.contributor.author | Jang, Won Hyuk | - |
dc.contributor.author | KIM, KI HEAN | - |
dc.contributor.author | Lee, Jun-Seok | - |
dc.contributor.author | Yoo, Jejoong | - |
dc.contributor.author | Kim, Sungwan | - |
dc.contributor.author | Kim, Kimoon | - |
dc.date.accessioned | 2018-05-04T02:33:16Z | - |
dc.date.available | 2018-05-04T02:33:16Z | - |
dc.date.created | 2018-03-05 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/41175 | - |
dc.description.abstract | Serendipitously, mono-allyloxylated cucurbit[7]uril (AO(1)CB[7]) was discovered to act as an unconventional amphiphile which self-assembles into light-responsive vesicles (AO(1)CB[7]VC) in water. Although the mono-allyloxy group, directly tethered on the periphery of CB[7], is much shorter (C4) than the hydrophobic tails of conventional amphiphiles, it played an important role in vesicle formation. Light-activated transformation of the allyloxy group by conjugation with glutathione was exploited as a remote tool to disrupt the vesicle. The vesicle showed on-demand release of cargo upon irradiation by a laser, after they were internalized into cancer cells. This result demonstrated the potential of AO(1)CB[7]VC as a new type of light-responsive intracellular delivery vehicle for the release of therapeutic cargo, within cells, on demand. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.relation.isPartOf | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.title | Mono-allyloxylated Cucurbit[7]uril Acts as an Unconventional Amphiphile to Form Light-Responsive Vesicles | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/anie.201713059 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.57, no.12, pp.3132 - 3136 | - |
dc.identifier.wosid | 000426759900021 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 3136 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 3132 | - |
dc.citation.title | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.citation.volume | 57 | - |
dc.contributor.affiliatedAuthor | Jang, Won Hyuk | - |
dc.contributor.affiliatedAuthor | KIM, KI HEAN | - |
dc.contributor.affiliatedAuthor | Kim, Sungwan | - |
dc.contributor.affiliatedAuthor | Kim, Kimoon | - |
dc.identifier.scopusid | 2-s2.0-85042217290 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 4 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | COMPLEXES | - |
dc.subject.keywordPlus | CHEMISTRY | - |
dc.subject.keywordPlus | PROTEINS | - |
dc.subject.keywordPlus | POLYMER | - |
dc.subject.keywordPlus | MOLECULAR RECOGNITION | - |
dc.subject.keywordPlus | PHOTODYNAMIC THERAPY | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | FRET PAIR | - |
dc.subject.keywordPlus | FUSION | - |
dc.subject.keywordAuthor | amphiphiles | - |
dc.subject.keywordAuthor | cucurbiturils | - |
dc.subject.keywordAuthor | drug delivery | - |
dc.subject.keywordAuthor | supramolecular chemistry | - |
dc.subject.keywordAuthor | vesicles | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
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