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Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor SCIE SCOPUS
- Title
- Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor
- Authors
- Vendrell, Marc; Krishna, Gaddamanugu Gopi; Ghosh, Krishna Kanta; Zhai, Duanting; Lee, Jun-Seok; Zhu, Qing; Yau, Yin Hoe; Shochat, Susana Geifman; Kim, Hyori; Chung, Junho; Chang, Young-Tae
- Date Issued
- 2011
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.
- Keywords
- COMBINATORIAL SYNTHESIS; CYANINE DYES; FUNCTIONALIZATION; DERIVATIVES; LIBRARY; CHEMISTRY; DESIGN; PROBE; BORON
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- CHEMICAL COMMUNICATIONS, vol. 47, no. 29, page. 8424 - 8426, 2011
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Related Researcher
- 장영태CHANG, YOUNG TAE
- Dept of Chemistry