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Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging SCIE SCOPUS
- Title
- Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging
- Authors
- Lee, Jae Hong; So, Ju-Hoon; Jeon, Jong Hyun; Choi, Eun Bok; Lee, Yu-Ri; Chang, Young-Tae; Kim, Cheol-Hee; Bae, Myung Ae; Ahn, Jin Hee
- Date Issued
- 2011
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- A new small molecule probe for in vivo lipid imaging, LipidGreen (compound 5), was developed. LipidGreen stained lipid droplets in 3T3L1 cell lines and fat deposits in zebrafish without apparent toxicity up to 100 mu M. The utility of LipidGreen as a drug screening platform for fat regulation was also demonstrated in live zebrafish.
- Keywords
- TRIGLYCERIDE SYNTHESIS; CELL BIOLOGY; NILE RED; DROPLETS; DGAT; FAT
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- CHEMICAL COMMUNICATIONS, vol. 47, no. 26, page. 7500 - 7502, 2011
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Related Researcher
- 장영태CHANG, YOUNG TAE
- Dept of Chemistry