DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Changsub | - |
dc.contributor.author | Kwon, Kyungho | - |
dc.contributor.author | Lee, Jongchan | - |
dc.contributor.author | Kim, Heesoo | - |
dc.contributor.author | Chae, Keun-Hwa | - |
dc.contributor.author | Ree, Moonhor | - |
dc.date.accessioned | 2018-06-15T05:36:38Z | - |
dc.date.available | 2018-06-15T05:36:38Z | - |
dc.date.created | 2017-10-10 | - |
dc.date.issued | 2017-09 | - |
dc.identifier.issn | 0024-9297 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/50655 | - |
dc.description.abstract | We have newly synthesized a series of well-defined brush polyethers bearing cholesterol (Chol) and phosphorylcholine (PC) moieties in various compositions which can mimic cell membrane. They were thermally stable up to at least 230 degrees C and soluble in common solvents, showing good solution processability. Excitingly, they all favorably self assembled, forming multibilayer structures with 2(1) chain conformation; in comparison, the brush polyether bearing only PC-bristles formed orthorhombically packed cylinder (OPC) structure with 12(5) helical chain conformation. Such multibilayer structure formations could be driven by a strong self-assembling ability of the Chol-bristle in extended conformation; the multibilayer structure formation was further promoted by the presence of PC-bristles. The OPC structure formation could be driven by a lateral packing ability of the brush polymer chain in the helical confirmation resulted from the minimization of repulsive interactions in the neighbored zwitterionic PC-bristles. Because of such the self-assembling natures, all brush polymers always revealed Chol- and PC-enriched surface. Overall, all brush polyethers of this study successfully mimicked cell membrane features (Chol- and PC-surface based on self assembling). They are very suitable for uses in the fields required cell membrane surface characteristics. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.relation.isPartOf | MACROMOLECULES | - |
dc.title | Well-Defined Biomimicking Brush-Polymer Self-Assemblies Revealing Cholesterol- and Phosphorylcholine-Enriched Surface | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/acs.macromol.7b00805 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | MACROMOLECULES, v.50, no.17, pp.6489 - 6500 | - |
dc.identifier.wosid | 000410867400014 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 6500 | - |
dc.citation.number | 17 | - |
dc.citation.startPage | 6489 | - |
dc.citation.title | MACROMOLECULES | - |
dc.citation.volume | 50 | - |
dc.contributor.affiliatedAuthor | Kim, Changsub | - |
dc.contributor.affiliatedAuthor | Lee, Jongchan | - |
dc.contributor.affiliatedAuthor | Ree, Moonhor | - |
dc.identifier.scopusid | 2-s2.0-85029351409 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 2 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CLICK CHEMISTRY | - |
dc.subject.keywordPlus | CELLS | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Polymer Science | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.