DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, K.M. | - |
dc.contributor.author | Kim, H. | - |
dc.contributor.author | Murray, J. | - |
dc.contributor.author | Koo, J. | - |
dc.contributor.author | Kim, K. | - |
dc.date.accessioned | 2018-07-17T10:45:16Z | - |
dc.date.available | 2018-07-17T10:45:16Z | - |
dc.date.created | 2017-12-21 | - |
dc.date.issued | 2017-06 | - |
dc.identifier.issn | 1061-0278 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/92095 | - |
dc.description.abstract | Tb-based metal-organic framework nanoparticles (Tb-MOF NPs) with good colloidal stability and stable fluorescence properties in an aqueous solution were prepared by a simple mechanical grinding of Tb-MOF with a biocompatible polymer surfactant (F127). The characteristic fluorescence property of Tb-MOF NPs allowed us to use this nanomaterial as a cell imaging probe. Efficient cellular uptake of Tb-MOF NPs apparently via an energy-dependent endocytosis was observed by confocal laser scanning microscopy. By taking advantage of the porous nature of the Tb-MOF NPs an anticancer drug (doxorubicin) was successfully loaded and delivered to kill cancer cells to demonstrate their usage as a drug delivery vehicle. This simple grinding method afforded a nanosized, multifunctional biomaterial that was used for cell imaging and drug delivery, and it can be extended to other MOFs to widen their applications. ? 2016 Informa UK Limited, trading as Taylor & Francis Group. | - |
dc.language | English | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.relation.isPartOf | SUPRAMOLECULAR CHEMISTRY | - |
dc.subject | Metal-organic framework | - |
dc.subject | nanoparticles | - |
dc.subject | bioimaging | - |
dc.subject | drug delivery | - |
dc.subject | endocytosis | - |
dc.title | A facile preparation method for nanosized MOFs as a multifunctional material for cellular imaging and drug delivery | - |
dc.type | Article | - |
dc.identifier.doi | 10.1080/10610278.2016.1266359 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | SUPRAMOLECULAR CHEMISTRY, v.29, no.6, pp.441 - 445 | - |
dc.identifier.wosid | 000396762300005 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 445 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 441 | - |
dc.citation.title | SUPRAMOLECULAR CHEMISTRY | - |
dc.citation.volume | 29 | - |
dc.contributor.affiliatedAuthor | Kim, K. | - |
dc.identifier.scopusid | 2-s2.0-85002323053 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 7 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | METAL-ORGANIC FRAMEWORKS | - |
dc.subject.keywordPlus | CARBON NANOTUBES | - |
dc.subject.keywordPlus | F127 | - |
dc.subject.keywordPlus | ENDOCYTOSIS | - |
dc.subject.keywordPlus | HYDROGEN | - |
dc.subject.keywordPlus | STORAGE | - |
dc.subject.keywordPlus | MEDIA | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordAuthor | Metal-organic framework | - |
dc.subject.keywordAuthor | nanoparticles | - |
dc.subject.keywordAuthor | bioimaging | - |
dc.subject.keywordAuthor | drug delivery | - |
dc.subject.keywordAuthor | endocytosis | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
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