Microfluidic-based cell handling devices for biochemical applications
SCIE
SCOPUS
- Title
- Microfluidic-based cell handling devices for biochemical applications
- Authors
- LEE, SANG HYUN; Kim, Ho-Jin; WONHYUNG, LEE; KIM, JOON WON
- Date Issued
- 2018-12
- Publisher
- IOP PUBLISHING LTD
- Abstract
- Microfluidic-based cell handling techniques have become promising tools for biochemical applications, and many such techniques have been developed with the advancement of microfabrication technologies. A microfluidic-based platform used for biochemical analysis offers numerous benefits, including small sample consumption, massive parallelization, rapid analysis, and the capability for single-cell analysis, which are difficult to achieve in conventional cell handling methods on a large scale. It also exhibits precise spatial and temporal control of the local cellular microenvironments based on microfluidic networks in accordance to the unique fluidic phenomena of microfluidics. This review focuses on various cell handling methods that take advantage of microfluidics by classifying them in accordance to specific functions required for biochemical analyses, including (i) cell transfer, (ii) cell separation and sorting, (iii) cell immobilization, (iv) cell isolation and encapsulation, and (v) cell retrieval.
- Keywords
- Cell immobilization; Lab-on-a-chip; Molecular biology; Bio-chemical applications; Biochemical analysis; Cell manipulation; Micro-fabrication technology; Microfluidic networks; Microfluidic-based; Singlecell analysis; Temporal controls; Microfluidics
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/94479
- DOI
- 10.1088/1361-6439/aae4fc
- ISSN
- 0960-1317
- Article Type
- Article
- Citation
- JOURNAL OF MICROMECHANICS AND MICROENGINEERING, vol. 28, no. 12, 2018-12
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.