Kakeromamide A, a new cyclic pentapeptide inducing astrocyte differentiation isolated from the marine cyanobacterium Moorea bouillonii
SCIE
SCOPUS
- Title
- Kakeromamide A, a new cyclic pentapeptide inducing astrocyte differentiation isolated from the marine cyanobacterium Moorea bouillonii
- Authors
- Nakamura, Fumiaki; Maejima, Hiroshi; Kawamura, Midori; Arai, Daisuke; Okino, Tatsufumi; Zhao, Meng; Ye, Tao; Lee, Jungyeol; Chang, Young-Tae; Fusetani, Nobuhiro; Nakao, Yoichi
- Date Issued
- 2018-07
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- Kakeromamide A (1), a new cyclic pentapeptide encompassing a thiazole ring moiety and a beta-amino acid, was isolated from the marine cyanobacterium Moorea bouillonii. Its structure was elucidated by the spectral analysis and the modified Marfey's method. Compound 1 induced differentiation of neural stem cells into astrocytes at the concentration of 10 mu M. (C) 2018 Published by Elsevier Ltd.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/95848
- DOI
- 10.1016/j.bmcl.2018.04.067
- ISSN
- 0960-894X
- Article Type
- Article
- Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 28, no. 12, page. 2206 - 2209, 2018-07
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