DC Field | Value | Language |
---|---|---|
dc.contributor.author | CHANG, YOUNG TAE | - |
dc.contributor.author | Chung, Sung-Kee | - |
dc.contributor.author | Sohn, Kwang-Hoon | - |
dc.date.accessioned | 2020-03-18T05:50:37Z | - |
dc.date.available | 2020-03-18T05:50:37Z | - |
dc.date.created | 2020-03-17 | - |
dc.date.issued | 1994-02 | - |
dc.identifier.issn | 1017-2548 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/101528 | - |
dc.description.abstract | myo-Inosiol-1,4,5-trisphosphate(1) is well established as a second messenger mobilizing Ca2+ in the intracellular signal transduction pathway. Compound 1 and its positional isomers, myo-Inositol 2,4,6-trisphosphate(2) and -1,3,5-trisphosphate(3) were synthesized from myo-inositol. An efficient synthetic pathway of 1 using myo-inositol-1,2,4-trisbenzoate(6) as the key intermediate, prepared from myo-inositol-1,4-bisbenzoate(5) by regioselective benzoylation at the axial 2-OH over the eqiuatorial 3-OH, is described. Syntheses of 2 and 3 utilizing the monoorthoformate derivative(8) of myo-inositol as the key intermediate are also reported. | - |
dc.language | English | - |
dc.publisher | Korean Chemical Society | - |
dc.relation.isPartOf | Journal of the Korean Chemical Society | - |
dc.title | Synthesis of myo-Inositol-1,4,5-2,4,6-and 1,3,5-trisphosphate | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Journal of the Korean Chemical Society, v.4, no.1, pp.57 - 65 | - |
dc.citation.endPage | 65 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 57 | - |
dc.citation.title | Journal of the Korean Chemical Society | - |
dc.citation.volume | 4 | - |
dc.contributor.affiliatedAuthor | CHANG, YOUNG TAE | - |
dc.contributor.affiliatedAuthor | Chung, Sung-Kee | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
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