DC Field | Value | Language |
---|---|---|
dc.contributor.author | Li, Xingshu | - |
dc.contributor.author | Park, Eun-Yeong | - |
dc.contributor.author | Kang, Youngnam | - |
dc.contributor.author | Kwon, Nahyun | - |
dc.contributor.author | Yang, Mengyao | - |
dc.contributor.author | Lee, Seunghyun | - |
dc.contributor.author | Kim, Won Jong | - |
dc.contributor.author | Kim, Chulhong | - |
dc.contributor.author | Yoon, Juyoung | - |
dc.date.accessioned | 2020-04-22T04:50:04Z | - |
dc.date.available | 2020-04-22T04:50:04Z | - |
dc.date.created | 2020-04-20 | - |
dc.date.issued | 2020-03 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/103565 | - |
dc.description.abstract | Phototheranostic nanoplatforms are of particular interest for cancer diagnosis and imaging-guided therapy. Herein, we develop a supramolecular approach to fabricate a nanostructured phototheranostic agent through the direct self-assembly of two water-soluble phthalocyanine derivatives, PcS4 and PcN4. The nature of the molecular recognition between PcS4 and PcN4 facilitates the formation of nanostructure (PcS4-PcN4) and consequently enables the fabrication of PcS4-PcN4 with completely quenched fluorescence and reduced singlet oxygen generation, leading to the high photoacoustic and photothermal activity of PcS4-PcN4. In vivo evaluations suggest that PcS4-PcN4 could not only efficiently visualize a tumor with high contrast through whole-body photoacoustic imaging but also enable excellent photothermal therapy for cancer. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.relation.isPartOf | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.subject | Diagnosis | - |
dc.subject | Diseases | - |
dc.subject | Fluorescence quenching | - |
dc.subject | Gas generators | - |
dc.subject | Molecular oxygen | - |
dc.subject | Nanostructures | - |
dc.subject | Photoacoustic effect | - |
dc.subject | Cancer diagnosis | - |
dc.subject | High contrast | - |
dc.subject | Nano-structured | - |
dc.subject | Photo-acoustic imaging | - |
dc.subject | Photothermal therapy | - |
dc.subject | phthalocyanine | - |
dc.subject | Phthalocyanine derivatives | - |
dc.subject | Singlet oxygen generation | - |
dc.subject | Supramolecular chemistry | - |
dc.title | Supramolecular Phthalocyanine Assemblies for Improved Photoacoustic Imaging and Photothermal Therapy | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/anie.201916147 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.identifier.wosid | 000520282000001 | - |
dc.citation.title | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.contributor.affiliatedAuthor | Park, Eun-Yeong | - |
dc.contributor.affiliatedAuthor | Kim, Won Jong | - |
dc.contributor.affiliatedAuthor | Kim, Chulhong | - |
dc.identifier.scopusid | 2-s2.0-85081951611 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article; Early Access | - |
dc.subject.keywordPlus | PHOTODYNAMIC THERAPY | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | PHOTOSENSITIZERS | - |
dc.subject.keywordPlus | STRATEGIES | - |
dc.subject.keywordPlus | BILAYERS | - |
dc.subject.keywordAuthor | nanostructures | - |
dc.subject.keywordAuthor | photoacoustic imaging | - |
dc.subject.keywordAuthor | photothermal therapy | - |
dc.subject.keywordAuthor | phthalocyanine | - |
dc.subject.keywordAuthor | supramolecular chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
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