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Cited 6 time in webofscience Cited 6 time in scopus
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3D bioprinted and integrated platforms for cardiac tissue modeling and drug testing SCIE SCOPUS

Title
3D bioprinted and integrated platforms for cardiac tissue modeling and drug testing
Authors
Yong, UijungKang, ByeongminJANG, JIN AH
Date Issued
2021-08
Publisher
Portland Press, Ltd.
Abstract
Abstract Recent advances in biofabrication techniques, including 3D bioprinting, have allowed for the fabrication of cardiac models that are similar to the human heart in terms of their structure (e.g., volumetric scale and anatomy) and function (e.g., contractile and electrical properties). The importance of developing techniques for assessing the characteristics of 3D cardiac substitutes in real time without damaging their structures has also been emphasized. In particular, the heart has two primary mechanisms for transporting blood through the body: contractility and an electrical system based on intra and extracellular calcium ion exchange. This review introduces recent trends in 3D bioprinted cardiac tissues and the measurement of their structural, contractile, and electrical properties in real time. Cardiac models have also been regarded as alternatives to animal models as drug-testing platforms. Thus, perspectives on the convergence of 3D bioprinted cardiac tissues and their assessment for use in drug development are also presented.
URI
https://oasis.postech.ac.kr/handle/2014.oak/109109
DOI
10.1042/ebc20200106
ISSN
0071-1365
Article Type
Article
Citation
Essays in Biochemistry, vol. 65, no. 3, page. 545 - 554, 2021-08
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장진아JANG, JIN AH
Dept of Mechanical Enginrg
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