DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, CS | - |
dc.contributor.author | Seo, JH | - |
dc.contributor.author | Kang, DG | - |
dc.contributor.author | Cha, HJ | - |
dc.date.accessioned | 2016-03-31T07:57:18Z | - |
dc.date.available | 2016-03-31T07:57:18Z | - |
dc.date.created | 2015-01-27 | - |
dc.date.issued | 2014-05 | - |
dc.identifier.issn | 0734-9750 | - |
dc.identifier.other | 2014-OAK-0000030781 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/14238 | - |
dc.description.abstract | The development of efficient tools is required for the eco-friendly detoxification and effective detection of neurotoxic organophosphates (OPs). Although enzymes have received significant attention as biocatalysts because of their high specific activity, the uneconomic and labor-intensive processes of enzyme production and purification make their broad use in practical applications difficult. Because whole7cell systems offer several advantages compared with free enzymes, including high stability, a reduced purification requirement, and low preparation cost, they have been suggested as promising biocatalysts for the detoxification and detection of OPs. To develop efficient whole-cell biocatalysts with enhanced activity and a broad spectrum of substrate specificity, several factors have been considered, namely the selected strains, the chosen OP-hydrolyzing enzymes, where enzymes are localized in a cell, and which enhancer will assist the expression, function, and folding of the enzyme. In this article, we review the current investigative progress in the development of engineered whole-cell biocatalysts with excellent OP-hydrolyzing activity, a broad spectrum of substrate specificity, and outstanding stability for the detoxification and detection of OPs. (C) 2014 Elsevier Inc. All rights reserved. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | ELSEVIER | - |
dc.relation.isPartOf | BIOTECHNOLOGY ADVANCES | - |
dc.title | Engineered whole-cell biocatalyst-based detoxification and detection of neurotoxic organophosphate compounds | - |
dc.type | Article | - |
dc.contributor.college | 화학공학과 | - |
dc.identifier.doi | 10.1016/J.BIOTECHADV.2014.04.010 | - |
dc.author.google | Kim, CS | - |
dc.author.google | Seo, JH | - |
dc.author.google | Kang, DG | - |
dc.author.google | Cha, HJ | - |
dc.relation.volume | 32 | - |
dc.relation.issue | 3 | - |
dc.relation.startpage | 652 | - |
dc.relation.lastpage | 662 | - |
dc.contributor.id | 10057405 | - |
dc.relation.journal | BIOTECHNOLOGY ADVANCES | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOTECHNOLOGY ADVANCES, v.32, no.3, pp.652 - 662 | - |
dc.identifier.wosid | 000337855400009 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 662 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 652 | - |
dc.citation.title | BIOTECHNOLOGY ADVANCES | - |
dc.citation.volume | 32 | - |
dc.contributor.affiliatedAuthor | Cha, HJ | - |
dc.identifier.scopusid | 2-s2.0-84900563223 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 10 | - |
dc.description.scptc | 9 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Review | - |
dc.subject.keywordPlus | RECOMBINANT ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | ICE-NUCLEATION PROTEIN | - |
dc.subject.keywordPlus | PSEUDOMONAS-PUTIDA JS444 | - |
dc.subject.keywordPlus | AMPEROMETRIC MICROBIAL BIOSENSOR | - |
dc.subject.keywordPlus | METHYL PARATHION HYDROLASE | - |
dc.subject.keywordPlus | CELLULOSE-BINDING DOMAIN | - |
dc.subject.keywordPlus | NERVE AGENTS | - |
dc.subject.keywordPlus | SURFACE-DISPLAY | - |
dc.subject.keywordPlus | SIMULTANEOUS DEGRADATION | - |
dc.subject.keywordPlus | P-NITROPHENOL | - |
dc.subject.keywordAuthor | Organophosphates | - |
dc.subject.keywordAuthor | Whole-cell biocatalyst | - |
dc.subject.keywordAuthor | Organophosphate-hydrolyzing enzyme | - |
dc.subject.keywordAuthor | Detoxification | - |
dc.subject.keywordAuthor | Detection | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
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