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TGF-Beta puts the brakes on homeostatic proliferation SCIE SCOPUS
- Title
- TGF-Beta puts the brakes on homeostatic proliferation
- Date Issued
- 2012-07
- Publisher
- Nature Publishing Group
- Abstract
- The cellular mechanism by which the cytokine TGF-beta maintains the homeostasis of mature T cells and prevents the emergence of severe lethal lymphoproliferative disease has remained obscure. It is now shown that TGF-b restrains the homeostatic T cell proliferation driven by self ligands from erupting into overt autoimmunity.
- Keywords
- T-CELLS; NAIVE; MECHANISMS; MICE
- ISSN
- 1529-2908
- Article Type
- Article
- Citation
- Nature Immunology, vol. 13, no. 7, page. 1032 - 1034, 2012-07
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Related Researcher
- SURH CHARLES DSURH, CHARLES D
- Div of Integrative Biosci & Biotech