Ultrasensitive detection of Ebola matrix protein in a memristor mode
SCIE
SCOPUS
- Title
- Ultrasensitive detection of Ebola matrix protein in a memristor mode
- Authors
- Bergoi Ibarlucea; Teuku Fawzul Akbar; Kihyun Kim; Taiuk Rim; BAEK, CHANG KI; Alon Ascoli; Ronald Tetzlaff; Larysa Baraban; Gianaurelio Cuniberti
- Date Issued
- 2018-02
- Publisher
- TSINGHUA UNIV PRESS
- Abstract
- We demonstrate the direct biosensing of the Ebola VP40 matrix protein, using a memristor mode of a liquid-integrated nanodevice, based on a large array of honeycomb-shaped silicon nanowires. To shed more light on the principle of biodetection using memristors, we engineered the opening of the current-minima voltage gap V-GAP by involving the third gap-control electrode (gate voltage, V-G) into the system. The primary role of V-G is to mimic the presence of the charged species of the desired sign at the active area of the sensor. We further showed the advantages of biodetection with an initially opened controlled gap (V-GAP not equal 0), which allows the detection of the lowest concentrations of the biomolecules carrying arbitrary positive or negative charges; this feature was not present in previous configurations. We compared the bio-memristor performance, in terms of its detection range and sensitivity, to that of the already-known field-effect transistor (FET) mode by operating the same device. To our knowledge, this is the first demonstration of Ebola matrix protein detection using a nanoscaled electrical sensor.
- Keywords
- memristor biosensor; capacitance; honeycomb nanowires; silicon nanowire field effect transistor; VP40 matrix protein; Ebola detection
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/41006
- DOI
- 10.1007/s12274-017-1720-2
- ISSN
- 1998-0124
- Article Type
- Article
- Citation
- Nano Research, vol. 11, no. 2, page. 1057 - 1068, 2018-02
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.