DC Field | Value | Language |
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dc.contributor.author | KIM, SUNGJEE | - |
dc.contributor.author | LEE, GYUDONG | - |
dc.contributor.author | JEONG, SANGHWA | - |
dc.contributor.author | KWON, DONGHOON | - |
dc.contributor.author | PARK, JOONHYUCK | - |
dc.contributor.author | JEON, SANGMIN | - |
dc.date.accessioned | 2018-05-11T00:26:22Z | - |
dc.date.available | 2018-05-11T00:26:22Z | - |
dc.date.created | 2018-03-03 | - |
dc.date.issued | 2017-11-28 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/42689 | - |
dc.description.abstract | The diagnosis and therapy of disease require information of multiple targets. In order to identify multiple biomolecule, an effective strategy for separation and multiplexing is important.1) A bio-barcoding system that incorporates quantum dots (QDs) and magnetic nanoparticles can be useful for such applications.2) Silica-shell-coated magnetic nanoparticle cluster (SMNC) were synthesized and the surface of SMNC was decorated by zwitterionic ligands, which made the SMNC colloidally stable at physiological condition and possess minimal non-specific adsorptions.3) Zwitterion tethered SMNC showed enhanced colloidal stability in high salt concentration and under broad pH range. The minimal non-specific adsorption was confirmed by non-specific adsorption level assays using fluorescein conjugated serum albumin. Also, SMNCs were loaded with QDs using amphiphilic polyethyleneimine derivatives (amPEIs). The resultant a few hundred nanometer sized SMNC-QDs-amPEIs were composed of SMNC core surrounded by hundreds of QDs. SMNC-QDs complexs showed excellent photoluminescene(PL) property and can be facilely collected in presence of an external magnetic field. These SMNC-QDs complexs and SMNC with reduced non-specific adsorption can be useful as bio- barcoding agent. | - |
dc.language | English | - |
dc.publisher | MRS | - |
dc.relation.isPartOf | 2017 MRS Fall Meeting & Exhibit | - |
dc.relation.isPartOf | 2017 MRS Fall Meeting & Exhibit | - |
dc.title | Surface Modification of Magnetic Nanoparticle Clusters for Biomedical Applications | - |
dc.type | Conference | - |
dc.type.rims | CONF | - |
dc.identifier.bibliographicCitation | 2017 MRS Fall Meeting & Exhibit | - |
dc.citation.conferenceDate | 2017-11-26 | - |
dc.citation.conferencePlace | US | - |
dc.citation.conferencePlace | Boston, Massachusetts | - |
dc.citation.title | 2017 MRS Fall Meeting & Exhibit | - |
dc.contributor.affiliatedAuthor | KIM, SUNGJEE | - |
dc.contributor.affiliatedAuthor | LEE, GYUDONG | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
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