DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jae Wook | - |
dc.contributor.author | Ha, Hyung-Ho | - |
dc.contributor.author | Vendrell, Marc | - |
dc.contributor.author | Bork, Jacqueline T. | - |
dc.contributor.author | Chang, Young-Tae | - |
dc.date.accessioned | 2018-06-15T05:12:49Z | - |
dc.date.available | 2018-06-15T05:12:49Z | - |
dc.date.created | 2017-09-08 | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0004-9425 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/50213 | - |
dc.description.abstract | A synthetic methodology to prepare collections of trisubstituted aryl 1,3,5-triazines with broad structural diversity via Suzuki coupling has been developed. We first optimized the combinatorial derivatization of the triazine core using Suzuki cross-coupling. Second, in order to further expand the methodology for the preparation of negatively charged triazines, we adapted this approach to polymer-supported amino acids and prepared aryl triazines with different charge distribution. With a collection of 160 aryl triazine derivatives in good purities and without any purification step, we proved the viability of this orthogonal scheme for the preparation of triazine libraries using amine/amino acid-captured solid supports and Suzuki cross-coupling. | - |
dc.language | English | - |
dc.publisher | CSIRO PUBLISHING | - |
dc.relation.isPartOf | AUSTRALIAN JOURNAL OF CHEMISTRY | - |
dc.subject | ORTHOGONAL SYNTHESIS | - |
dc.subject | TRIAZINE LIBRARY | - |
dc.subject | ANTITUMOR EVALUATION | - |
dc.subject | KINASE INHIBITORS | - |
dc.subject | SERIES | - |
dc.subject | HETEROCYCLES | - |
dc.subject | DERIVATIVES | - |
dc.subject | MODULATORS | - |
dc.subject | ANALOGS | - |
dc.title | Combinatorial Solid-Phase Synthesis of 6-Aryl-1,3,5-triazines via Suzuki Coupling | - |
dc.type | Article | - |
dc.identifier.doi | 10.1071/CH11034 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | AUSTRALIAN JOURNAL OF CHEMISTRY, v.64, no.5, pp.540 - 544 | - |
dc.identifier.wosid | 000291058100007 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 544 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 540 | - |
dc.citation.title | AUSTRALIAN JOURNAL OF CHEMISTRY | - |
dc.citation.volume | 64 | - |
dc.contributor.affiliatedAuthor | Chang, Young-Tae | - |
dc.identifier.scopusid | 2-s2.0-79957877724 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 3 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | ORTHOGONAL SYNTHESIS | - |
dc.subject.keywordPlus | TRIAZINE LIBRARY | - |
dc.subject.keywordPlus | ANTITUMOR EVALUATION | - |
dc.subject.keywordPlus | KINASE INHIBITORS | - |
dc.subject.keywordPlus | SERIES | - |
dc.subject.keywordPlus | HETEROCYCLES | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | MODULATORS | - |
dc.subject.keywordPlus | ANALOGS | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
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